Solid Dispersion: A Mechanistic and Realistic Approach on Antihypertensive Drug as a Drug Carrier System
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چکیده
منابع مشابه
Drug - Drug Solid Dispersion: A Unique Approach in Solubility Enhancement
Over 40% of active pharmaceutical ingredients in development are poorly water soluble drugs which limit formulation approaches, clinical application and marketability because of their low dissolution and bioavailability. Solid dispersion has been considered one of the major advancements in overcoming these issues with several successfully marketed products. Extensive review of the literature in...
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In this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. The effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...
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ژورنال
عنوان ژورنال: ASSAY and Drug Development Technologies
سال: 2021
ISSN: 1540-658X,1557-8127
DOI: 10.1089/adt.2020.1055